Mechanism of action of thrombin on fibrinogen. I. Synthesis of fibrinogen-like peptides, and their proteolysis by thrombin and trypsin.

Abstract

In a study of the action of thrombin on fibrinogen and a comparison of this enzyme with trypsin, several fibrinogen-like oligopeptides were synthesized. The hydrolysis of the arginyl-glycine bond in these peptides, by both of these enzymes, is examined and compared. 

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Cite this paper

@article{Andreatta1971MechanismOA, title={Mechanism of action of thrombin on fibrinogen. I. Synthesis of fibrinogen-like peptides, and their proteolysis by thrombin and trypsin.}, author={Rossana Andreatta and Ronald K. H. Liem and Harold A. Scheraga}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1971}, volume={68 2}, pages={253-6} }