Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1.

  title={Mechanism of action of sphingolipids and their metabolites in the toxicity of fumonisin B1.},
  author={J. M. Soriano and Lillian Gonz{\'a}lez and Angel Catala},
  journal={Progress in lipid research},
  volume={44 6},
Fumonisins are a group of mycotoxins produced primarily by Fusarium moniliforme. Several fumonisins have been isolated through out the years but only fumonisin B1, B2 and B3 are the ones present in naturally contaminated foods, with B1 being the most toxic between them. The structural similarity between sphinganine and fumonisin B1 suggests that the mechanism of action of this mycotoxin is mainly via disruption of sphingolipid metabolism, this is an important step in the cascade of events… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 49 extracted citations

Influence on functional parameters of intestinal tract induced by short-term exposure to fumonisins contaminated corn chyme samples.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2014
View 4 Excerpts
Highly Influenced

Fumonisins, Trichothecenes and Zearalenone in Cereals

International journal of molecular sciences • 2008
View 4 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 12 references

Cytokine 1999;11:839–48

E Kontny, M Ziolkowska, A Ryzewska, W. Maslinski
View 12 Excerpts
Highly Influenced

Toxicol Appl Pharm 1996;141:178–84

JM Yeung, HY Wang, DB. Prelusky
Progress in Lipid Research • 2005
View 1 Excerpt

The fifty-sixth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) Editor. Safety evaluation of certain mycotoxins

M Bolger, RD Coker, +3 authors M Olsen
View 1 Excerpt

Methods Enzymol 2000;312:361–73

ER Smith, AH Merrill, LM Obeid, YA. Hannum
View 1 Excerpt

Cardiovasc Res 1999;44:536–42

CA Piot, JF Martini, SK Bui, CL. Wolfe
View 1 Excerpt

Poultry Sci 1999;78:1275–82

YC Li, DR Ledoux, AJ Bermudez, KL Fritsche, GE. Rottinghaus
View 1 Excerpt

Tumor necrosis factor. In: Thomson AW, editor. The cytokine handbook

M Zhang, KJ Tracey
San Diego (CA): Academic Press; • 1998
View 3 Excerpts

Food Chem Toxicol 1994;32:489–91

GS Shepard, PG Thiel, EW Sydenham, JF. Alberts

Advances in lipid research: sphingolipids and their metabolites, vol. 26

AH Merrill, G Van Echten, +3 authors editors
View 1 Excerpt

Similar Papers

Loading similar papers…