Mechanism of action of reserpine on the pituitary — Adrenal cortex system

Abstract

According to repor ts in the l i tera ture [1 ,4-10 ,18 , 19], monoamines of the central nervous sys tem (especially of the hypothalamus) possibly play a role in regulating the adrenocor t icot ropic (ACT) function of the pituitary. Conclusions that catecholamines (CA) of the hypothalamus part icipate in regulation of pituitary ACT function were based on experiments with reserpine, a substance exhausting monoamine r e s erves in the t issues , and are highly contradictory [2, 9-12, 14, 17]. The reason for this is that the compound was given by different methods and ia different doses, and different tests were used to a s ses s the results at different t imes.

DOI: 10.1007/BF00788103

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Cite this paper

@article{Shchedrina2004MechanismOA, title={Mechanism of action of reserpine on the pituitary — Adrenal cortex system}, author={R. N. Shchedrina}, journal={Bulletin of Experimental Biology and Medicine}, year={2004}, volume={69}, pages={660-663} }