Mechanism of action of CCK in avian gastroduodenal motility: evidence for nitric oxide involvement.

@article{Martinez1993MechanismOA,
  title={Mechanism of action of CCK in avian gastroduodenal motility: evidence for nitric oxide involvement.},
  author={V. Martinez and Marcel Jimenez and Eduard Go{\~n}alons and Patricia Vergara},
  journal={The American journal of physiology},
  year={1993},
  volume={265 5 Pt 1},
  pages={G842-50}
}
Our objective was to study the mechanism of action of cholecystokinin (CCK) on the motility of the gastroduodenal area. Chickens were implanted with five electrodes for electromyography in the stomach and duodenum. The effects of CCK (10(-9) mol.kg-1.10 min-1) were studied against the presence of several antagonists and in vagotomized animals. CCK caused inhibition of gastric motility and duodenal hyperactivity. Vagotomy blocked CCK responses in the stomach but not in the duodenum… CONTINUE READING