Mechanism of action of 8-OH-DPAT on learning and memory.


It has been previously demonstrated that pretraining injection of 8-hydroxy-2-(di-n-propilamino)tetralin (8-OH-DPAT, a 5-HT1A agonist) impairs conditioned response (CR) in an autoshaping learning task. Therefore, in the present work we intended to determine whether such an effect could be prevented by pretraining, and whether pre- or postsynaptic 5-HT… (More)


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@article{Meneses1994MechanismOA, title={Mechanism of action of 8-OH-DPAT on learning and memory.}, author={Antonio Gonz{\'a}lez Meneses and Emily L. Hong}, journal={Pharmacology, biochemistry, and behavior}, year={1994}, volume={49 4}, pages={1083-6} }