Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells

@inproceedings{Akhade2016MechanismOW,
  title={Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells},
  author={Vijay Suresh Akhade and Shrinivas Nivrutti Dighe and Shubhangini Kataruka and Manchanahalli R. Satyanarayana Rao},
  booktitle={Nucleic acids research},
  year={2016}
}
Long non coding RNAs (lncRNAs) have emerged as important regulators of various biological processes. LncRNAs also behave as response elements or targets of signaling pathway(s) mediating cellular function. Wnt signaling is important in regulating mammalian spermatogenesis. Mrhl RNA negatively regulates canonical Wnt pathway and gets down regulated upon Wnt signaling activation in mouse spermatogonial cells. Also, mrhl RNA regulates expression of genes pertaining to Wnt pathway and… CONTINUE READING
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