Mechanism of Puberty

  title={Mechanism of Puberty},
  author={C. G. D. Brook},
  journal={Hormone Research in Paediatrics},
  pages={52 - 54}
  • C. Brook
  • Published 1 November 1999
  • Biology, Medicine
  • Hormone Research in Paediatrics
The hypothalamo-pituitary-gonadal axis in children is fully functional in fetal life and immediately after birth. The reason why it declines with advancing years of childhood is not clear but gonadotropin pulsatility is at a nadir at 6 years of age. From that time pulsatile gonadotropin starts to reappear but, again, the reason why this happens is completely unknown. All of the events of puberty can be ascribed to pulsatile gonadotropin-releasing hormone stimulation causing pulsatile… 
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