Mechanism of Interaction of Vitamin E and Glutathione in the Protection against Membrane Lipid Peroxidation

@article{Scholz1989MechanismOI,
  title={Mechanism of Interaction of Vitamin E and Glutathione in the Protection against Membrane Lipid Peroxidation},
  author={Richard W. Scholz and Kenneth S. Graham and Eric Gumpricht and C. Channa Reddy},
  journal={Annals of the New York Academy of Sciences},
  year={1989},
  volume={570}
}
Although the function of vitamin E as the major, if not only, chain-breaking, lipidsoluble antioxidant in biological membranes has been established,’ its mode( s) of action has yet to be elucidated. One proposed mechanism of vitamin E function involves a possible glutathione-dependent system that inhibits in vitro lipid peroxidation. Previously, we have described a rat liver microsomal system that inhibited both enzymatic and nonenzymatic lipid peroxidation in the presence of both glutathione… Expand
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TLDR
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