Mechanism of IFN-γ in regulating OPN/Th17 pathway during vascular collagen remodeling of hypertension induced by ANG II.

@article{Jiang2015MechanismOI,
  title={Mechanism of IFN-γ in regulating OPN/Th17 pathway during vascular collagen remodeling of hypertension induced by ANG II.},
  author={Lei Jiang and Pengcheng He and Yong Liu and Ji-Yan Chen and Xuebiao Wei and Ning Tan},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 11},
  pages={14433-40}
}
More and more researches show that hypertensive vascular remodeling is closely related to the imbalance of immune system in recent years. IFN-γ is natural protein with the function of immune regulation and has resistance effect on vascular remodeling. However, the mechanism of IFN-γ is to be defined. This paper is to explore the mechanism of IFN-γ in… CONTINUE READING