Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2.

Abstract

Basic leucine zipper (bZip) transcription factors regulate cellular gene expression in response to a variety of extracellular signals and nutrient cues. Although the bZip domain is widely known to play significant roles in DNA binding and dimerization, recent studies point to an additional role for this motif in the recruitment of the transcriptional… (More)
DOI: 10.1073/pnas.1219028109

Cite this paper

@article{Luo2012MechanismOC, title={Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2.}, author={Qianyi Luo and Kristin Viste and Janny Concha Urday-Zaa and Ganesan Senthil Kumar and Wen-Wei Tsai and Afsaneh Talai and Kelly E. Mayo and Marc R. Montminy and Ishwar Radhakrishnan}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2012}, volume={109 51}, pages={20865-70} }