Mechanism of Action and Applications of Interleukin 24 in Immunotherapy

  title={Mechanism of Action and Applications of Interleukin 24 in Immunotherapy},
  author={Leah Persaud and Dayenny De Jesus and Oliver Brannigan and Maria Richiez-Paredes and Jeannette Huaman and Giselle Alvarado and Linda Riker and Gissete Mendez and Jordan Dejoie and Moira Sauane},
  booktitle={International journal of molecular sciences},
Interleukin 24 (IL-24) is an important pleiotropic immunoregulatory cytokine, whose gene is located in human chromosome 1q32-33. IL-24's signaling pathways have diverse biological functions related to cell differentiation, proliferation, development, apoptosis, and inflammation, placing it at the center of an active area of research. IL-24 is well known for its apoptotic effect in cancer cells while having no such effect on normal cells. IL-24 can also be secreted by both immune and non-immune… CONTINUE READING


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