Mechanism of β- adrenergic relaxation of smooth muscle

  title={Mechanism of β- adrenergic relaxation of smooth muscle},
  author={Cheryl R. Scheid and Thomas W. Honeyman and Fredric S. Fay},
The mechanism of β-adrenergic relaxation was investigated in isolated smooth muscle cells. β-adrenergic agents stimulate cyclic AMP-dependent phosphorylation, enhance Na+/K+ transport and induce relaxation. The stimulation of Na+/K+ transport is obligatory for relaxation, and we suggest that this stimulation induces relaxation through enhanced Na+/Ca2+ exchange. 
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