Mechanism of α-ketol-type rearrangement of benzoin derivatives under basic conditions.

@article{Karino2013MechanismO,
  title={Mechanism of α-ketol-type rearrangement of benzoin derivatives under basic conditions.},
  author={Masahiro Karino and Daiki Kubouchi and Kazuki Hamaoka and Shintaro Umeyama and Hiroshi Yamataka},
  journal={The Journal of organic chemistry},
  year={2013},
  volume={78 14},
  pages={7194-8}
}
The mechanism of base-catalyzed rearrangement of ring-substituted benzoins in aqueous methanol was examined by kinetic and product analyses. Substituent effects on the rate and equilibrium constants revealed that the kinetic process has a different electron demand compared to the equilibrium process. Reactions in deuterated solvents showed that the rate of… CONTINUE READING