Mechanism for substance P-induced relaxation of precontracted airway smooth muscle during development.

Abstract

Release of substance P (SP) from sensory nerve endings of the tracheobronchial system modulates airway smooth muscle contraction and may cause relaxation of precontracted airways. We sought to elucidate the effect of postnatal maturation on SP-induced relaxation of precontracted airways and determine the roles of endogenously generated nitric oxide (NO) and… (More)

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@article{Mhanna1999MechanismFS, title={Mechanism for substance P-induced relaxation of precontracted airway smooth muscle during development.}, author={Maroun Jean Mhanna and Ismail A. Dreshaj and Musa A. Haxhiu and R. J. Martin}, journal={The American journal of physiology}, year={1999}, volume={276 1 Pt 1}, pages={L51-6} }