Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways

@article{Miller1999MechanismAF,
  title={Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways},
  author={Jeffrey R. Miller and Anne M. Hocking and Jeffrey D. Brown and Randall T. Moon},
  journal={Oncogene},
  year={1999},
  volume={18},
  pages={7860-7872}
}
Communication between cells is often mediated by secreted signaling molecules that bind cell surface receptors and modulate the activity of specific intracellular effectors. The Wnt family of secreted glycoproteins is one group of signaling molecules that has been shown to control a variety of developmental processes including cell fate specification, cell proliferation, cell polarity and cell migration. In addition, mis-regulation of Wnt signaling can cause developmental defects and is… CONTINUE READING
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