Mechanism and Prevention of Aminoglycoside Ototoxicity: Outer Hair Cells as Targets and Tools

@article{Priuska1997MechanismAP,
  title={Mechanism and Prevention of Aminoglycoside Ototoxicity: Outer Hair Cells as Targets and Tools},
  author={Eric M. Priuska and Jochen Schacht},
  journal={ENT Journal},
  year={1997},
  volume={76},
  pages={164 - 172}
}
Ototoxicity and Outer Hair Cells Apparent tissueand cell-specificity is considered one of the intriguing features of the toxic side effects of aminoglycoside ant ibiotics. The kidney and inner ear are affected, and within the inner ear it is the cochlear and vesti bular sensory epithelia that are damaged. Wi thin the cochlea, the outer hair cells are the preferential targets . Whi le such a "preference" for outer hair cells is frequently stressed in discussions of ototoxicity, it needs to be… Expand
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