Mechanism, prevention and therapy of sodium-dependent hypertension.

  title={Mechanism, prevention and therapy of sodium-dependent hypertension.},
  author={Francis J. Haddy},
  journal={The American journal of medicine},
  volume={69 5},
This review considers the mechanism, prevention and therapy of sodium-dependent, low-renin, presumably volume-expanded, hypertension. Certain evidence suggests that in susceptible persons the basic problem is a genetic or acquired deficiency in the ability of the kidney to excrete sodium and hence water. This places them at a disadvantage in a society such as ours in which the salt intake is uniformly high, to a large extent because of the salt content in commercially processed foods. Other… CONTINUE READING