Mechanisims of asthma and allergic disease – 1090. Eosinophils enhance airway smooth muscle cell proliferation via the release of cystl leukotrines


Background Asthma is a chronic inflammatory disorder of the lung airways that is associated with airway remodeling and hyperresponsiveness. Its is well documented that the smooth muscle mass in asthmatic airways is increased due to hypertrophy and hyperplasia of the ASM cells. Moreover, eosinophils have been proposed in different studies to play a major… (More)