Mechanics of active contraction in cardiac muscle: Part I--Constitutive relations for fiber stress that describe deactivation.

@article{Guccione1993MechanicsOA,
  title={Mechanics of active contraction in cardiac muscle: Part I--Constitutive relations for fiber stress that describe deactivation.},
  author={Julius M. Guccione and A. D. MCCULLOCH},
  journal={Journal of biomechanical engineering},
  year={1993},
  volume={115 1},
  pages={72-81}
}
Constitutive relations for active fiber stress in cardiac muscle are proposed and parameters are found that allow these relations to fit experimental data from the literature, including the tension redeveloped following rapid deactivating length perturbations. Contraction is driven by a length-independent free calcium transient. The number of actin sites available to react with myosin is determined from the total number of actin sites (available and inhibited), free calcium and the length… CONTINUE READING

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