Mechanics and polarity in cell motility

  title={Mechanics and polarity in cell motility},
  author={D. Ambrosi and Anna Zanzottera},
The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the nonmigrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in magnitude and direction. Transition from a stable configuration to the other one can be produced by a mechanical or chemotactic perturbation. In order to point out the mechanical nature of such a bistable behaviour, we focus on the actin dynamics inside the cell… CONTINUE READING
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