Mechanics and Dynamics of X-Chromosome Pairing at X Inactivation

Abstract

At the onset of X-chromosome inactivation, the vital process whereby female mammalian cells equalize X products with respect to males, the X chromosomes are colocalized along their Xic (X-inactivation center) regions. The mechanism inducing recognition and pairing of the X's remains, though, elusive. Starting from recent discoveries on the molecular factors… (More)
DOI: 10.1371/journal.pcbi.1000244

Topics

7 Figures and Tables

Slides referencing similar topics