Mechanics Regulates Fate Decisions of Human Embryonic Stem Cells

Abstract

Research on human embryonic stem cells (hESCs) has attracted much attention given their great potential for tissue regenerative therapy and fundamental developmental biology studies. Yet, there is still limited understanding of how mechanical signals in the local cellular microenvironment of hESCs regulate their fate decisions. Here, we applied a… (More)
DOI: 10.1371/journal.pone.0037178

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