Mechanical ventilation promotes lung metastasis in experimental 4T1 breast cancer lung-metastasized models

@inproceedings{Huang2018MechanicalVP,
  title={Mechanical ventilation promotes lung metastasis in experimental 4T1 breast cancer lung-metastasized models},
  author={Yinglai Huang and Lin Pan and Khalil Helou and Qisheng Xia and Toshima Z. Parris and Hongyan Li and Bo Xu and Hon gwei Li},
  booktitle={Cancer management and research},
  year={2018}
}
Background/purpose The aim of this study was to test the hypothesis that mechanical ventilation (MV) during cancer surgery induces lung stroma/tissue milieu changes, creating a favorable microenvironment for postoperative lung metastatic tumor establishment. Materials and methods In Protocol A, female BALB/c mice were divided into an MV group and a control (no MV) group, both of which were anesthetized and subjected to intravenous injection of green fluorescent protein (GFP)-labeled mouse… CONTINUE READING

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