Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia

@article{Dhanireddy2006MechanicalVI,
  title={Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia},
  author={Shireesha Dhanireddy and William A Altemeier and Gustavo Matute-Bello and Deborah O'mahony and Robb W. Glenny and Thomas R. Martin and W Conrad Liles},
  journal={Laboratory Investigation},
  year={2006},
  volume={86},
  pages={790-799}
}
Mechanical ventilation (MV) is frequently employed for the management of critically ill patients with respiratory failure. A major complication of mechanical ventilation (MV) is the development of ventilator-associated pneumonia (VAP), in which Staphylococcus aureus is a prominent pathogen. Moreover, previous studies suggest that MV may be an important cofactor in the development of acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS). S. aureus pulmonary infection was… CONTINUE READING
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