Mechanical ventilation affects alveolar fibrinolysis in LPS-induced lung injury

@article{Dahlem2006MechanicalVA,
  title={Mechanical ventilation affects alveolar fibrinolysis in LPS-induced lung injury},
  author={Peter Dahlem and Albert P. Bos and Jack J. Haitsma and Marcus J. Schultz and E. K. Wolthuis and Joost C. M. Meijers and Burkhard Lachmann},
  journal={European Respiratory Journal},
  year={2006},
  volume={28},
  pages={992 - 998}
}
The aim of the present study was to determine the effects of mechanical ventilation on alveolar fibrin turnover in lipopolysaccharide (LPS)-induced lung injury. In a randomised controlled trial, Sprague–Dawley rats (n = 61) were allocated to three ventilation groups after intratracheal LPS (Salmonella enteritidis) instillations. Group I animals were subjected to 16 cmH2O positive inspiratory pressure (PIP) and 5 cmH2O positive end-expiratory pressure (PEEP); group II animals to 26 cmH2O PIP and… 
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30 Citations
Background Citations
10
Methods Citations
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Results Citations
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30 Citations

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Citation Type

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TLDR
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