Mechanical response of individual collagen fibrils in loaded tendon as measured by atomic force microscopy.

@article{Rigozzi2011MechanicalRO,
  title={Mechanical response of individual collagen fibrils in loaded tendon as measured by atomic force microscopy.},
  author={Samuela Rigozzi and Andreas Stemmer and Reto Mueller and Jess Gerrit Snedeker},
  journal={Journal of structural biology},
  year={2011},
  volume={176 1},
  pages={9-15}
}
A precise analysis of the mechanical response of collagen fibrils in tendon tissue is critical to understanding the ultrastructural mechanisms that underlie collagen fibril interactions (load transfer), and ultimately tendon structure-function. This study reports a novel experimental approach combining macroscopic mechanical loading of tendon with a morphometric ultrascale assessment of longitudinal and cross-sectional collagen fibril deformations. An atomic force microscope was used to… CONTINUE READING
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