Mechanical regulation of chondrogenesis

  title={Mechanical regulation of chondrogenesis},
  author={C. O’Conor and N. Case and F. Guilak},
  journal={Stem Cell Research & Therapy},
  pages={61 - 61}
  • C. O’Conor, N. Case, F. Guilak
  • Published 2013
  • Medicine, Biology
  • Stem Cell Research & Therapy
  • Mechanical factors play a crucial role in the development of articular cartilage in vivo. In this regard, tissue engineers have sought to leverage native mechanotransduction pathways to enhance in vitro stem cell-based cartilage repair strategies. However, a thorough understanding of how individual mechanical factors influence stem cell fate is needed to predictably and effectively utilize this strategy of mechanically-induced chondrogenesis. This article summarizes some of the latest findings… CONTINUE READING
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