Mechanical properties of skinned single muscle fibers crosslinked with glutaraldehyde.


It was shown earlier (Mikawa 1979; Prochniewicz 1979) that crosslinking of thin filaments in vitro by glutaraldehyde can "'freeze'" their structure either in the activated (in the presence of Ca"-ions) or depressed (in the absence of C a t ions) state. This treatment does not inhibit the ability of actin to bind to myosin heads and to activate myosin ATPase… (More)


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