Mechanical properties of normal andmdx mouse sarcolemma: Bearing on function of dystrophin

@article{Hutter1991MechanicalPO,
  title={Mechanical properties of normal andmdx mouse sarcolemma: Bearing on function of dystrophin},
  author={Otto F. Hutter and Francis L. Burton and Douglas L Bovell},
  journal={Journal of Muscle Research & Cell Motility},
  year={1991},
  volume={12},
  pages={585-589}
}
The tensile strength of the muscle fibre surface membrane was estimated (1) from the suction required to burst membrane patches and (2) by aspiration of sarcolemmal vesicles into micropipettes of uniform bore. Each method gave an average value close to 60 μN cm−1 for the maximum tension sustainable by normal mouse sarcolemma and only slightly lower values for sarcolemma frommdx mice which lack dystrophin. The elastic modulus of area expansion, as measurable by pipette aspiration of sarcolemmal… CONTINUE READING