Mechanical properties of asthmatic airway smooth muscle.

@article{Chin2012MechanicalPO,
  title={Mechanical properties of asthmatic airway smooth muscle.},
  author={Leslie Y. M. Chin and Ynuk Boss{\'e} and Chris D Pascoe and Tillie L. Hackett and Chun Y Seow and Peter D. Par{\'e}},
  journal={The European respiratory journal},
  year={2012},
  volume={40 1},
  pages={
          45-54
        }
}

• Leslie Y. M. Chin, Ynuk Bossé, +3 authors Peter D. Paré
• Published 2012 in The European respiratory journal
• DOI:10.1183/09031936.00065411

Airway smooth muscle (ASM) is the major effector of excessive airway narrowing in asthma. Changes in some of the mechanical properties of ASM could contribute to excessive narrowing and have not been systematically studied in human ASM from nonasthmatic and asthmatic subjects. Human ASM strips (eight asthmatic and six nonasthmatic) were studied at in situ length and force was normalised to maximal force induced by electric field stimulation (EFS). Measurements included: passive and active force… CONTINUE READING

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