Mechanical loading triggers specific biochemical responses in mandibular condylar chondrocytes.

@article{Basdra1994MechanicalLT,
  title={Mechanical loading triggers specific biochemical responses in mandibular condylar chondrocytes.},
  author={Efthimia K. Basdra and Lukas A. Huber and Gerda Komposch and Athanasios G. Papavassiliou},
  journal={Biochimica et biophysica acta},
  year={1994},
  volume={1222 2},
  pages={315-22}
}
The effect of mechanical loading on the phosphorylation state of condylar cartilage proteins was investigated by high resolution electrophoretic analysis of 32P-labelled proteins from mechanically stimulated rat mandibular condylar chondrocytes. Specific dephosphorylation (and/or loss) of an acidic, 35-36 kDa protein(s) and of proteins overlapping with members of the ras superfamily of small GTP-binding proteins was observed. These responses may constitute part of a mechanically induced… CONTINUE READING

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