Mechanical load plays little role in contraction-mediated glucose transport in mouse skeletal muscle.

@article{Sandstrm2007MechanicalLP,
  title={Mechanical load plays little role in contraction-mediated glucose transport in mouse skeletal muscle.},
  author={Marie E. Sandstr{\"o}m and Shi-Jin Zhang and H{\aa}kan Westerblad and Abram Katz},
  journal={The Journal of physiology},
  year={2007},
  volume={579 Pt 2},
  pages={
          527-34
        }
}
The factors responsible for control of glucose transport during exercise are not fully understood. We investigated the role of mechanical load in contraction-mediated glucose transport in an isolated muscle preparation. Mouse extensor digitorum longus muscles were stimulated with repeated contractions for 10 min with or without N-benzyl-p-toluene sulphonamide (BTS, an inhibitor of myosin II ATPase) to block crossbridge activity. BTS inhibited force production during repeated contraction to… CONTINUE READING

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