Mechanical elasticity as a physical signature of conformational dynamics in a virus particle.

@article{Castellanos2012MechanicalEA,
  title={Mechanical elasticity as a physical signature of conformational dynamics in a virus particle.},
  author={Milagros Castellanos and Rebeca P{\'e}rez and Carolina Avila Carrasco and Mercedes Hernando-P{\'e}rez and Julio G{\'o}mez-Herrero and Pedro J de Pablo and Mauricio G Mateu},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 30},
  pages={12028-33}
}
In this study we test the hypothesis that mechanically elastic regions in a virus particle (or large biomolecular complex) must coincide with conformationally dynamic regions, because both properties are intrinsically correlated. Hypothesis-derived predictions were subjected to verification by using 19 variants of the minute virus of mice capsid. The… CONTINUE READING