Mechanical determinants of bone modeling.

  title={Mechanical determinants of bone modeling.},
  author={Harold M. Frost},
  journal={Metabolic bone disease & related research},
  volume={4 4},
In angulated long bone malunions in children, bone architectural changes arise which act consistently in kind, location, and direction, while the associated bone strain-stress patterns become definable as qualitative differences from the norm. Comparison of such information reveals that bone architectural adaptations correlate one-to-one with dynamic flexural strain orientation and magnitude but not with any single principal stress. The above plus other facts suggest six axioms which can… CONTINUE READING
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