Mechanical deactivation induced by active shortening in isolated muscle fibres of the frog.

@article{Edman1975MechanicalDI,
  title={Mechanical deactivation induced by active shortening in isolated muscle fibres of the frog.},
  author={K. A. P. Edman},
  journal={The Journal of physiology},
  year={1975},
  volume={246 1},
  pages={255-75}
}
1. The effect of active shortening on the time course and magnitude of isometric tension development during a single twitch and during an incompletely fused tetanus was studied at 0-2-1-2 degres C in isolated semitendinosus muscle fibres of the frog. 2. Active shortening caused a depression of the contractile force without markedly affecting the total duration of the twitch. The depressant effect increased with increasing amounts of sarcomere shortening. Sarcomere shortenings of 0-05 mum and 0… CONTINUE READING