Mechanical characterization of self-assembling peptide hydrogels by microindentation.

  title={Mechanical characterization of self-assembling peptide hydrogels by microindentation.},
  author={Nathan Allen Hammond and Roger D Kamm},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={101 6},
Hydrogels formed from self-assembling synthetic oligopeptides have been studied for almost 2 decades for use in tissue engineering and drug delivery. Although a great deal has been learned about the microstructure of these materials, there remain questions about how peptide filaments are ordered to form a gel. These unanswered questions leave a disconnect between our understanding of the observed nanoscale mechanical properties of peptide filaments and the macroscale properties of the gels they… CONTINUE READING