Mechanical Properties of Membranes Composed of Gel-Phase or Fluid-Phase Phospholipids Probed on Liposomes by Atomic Force Spectroscopy.

@article{EtThakafy2017MechanicalPO,
  title={Mechanical Properties of Membranes Composed of Gel-Phase or Fluid-Phase Phospholipids Probed on Liposomes by Atomic Force Spectroscopy.},
  author={Oumaima Et-Thakafy and N. Delorme and C{\'e}dric Gaillard and Cristelle M{\'e}riadec and Franck Artzner and Christelle Lopez and Fanny Guyomarc'h},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2017},
  volume={33 21},
  pages={
          5117-5126
        }
}
In many liposome applications, the nanomechanical properties of the membrane envelope are essential to ensure, e.g., physical stability, protection, or penetration into tissues. Of all factors, the lipid composition and its phase behavior are susceptible to tune the mechanical properties of membranes. To investigate this, small unilamellar vesicles (SUV; diameter < 200 nm), referred to as liposomes, were produced using either unsaturated 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) or… CONTINUE READING