Mechanical Network in Titin Immunoglobulin from Force Distribution Analysis

Abstract

The role of mechanical force in cellular processes is increasingly revealed by single molecule experiments and simulations of force-induced transitions in proteins. How the applied force propagates within proteins determines their mechanical behavior yet remains largely unknown. We present a new method based on molecular dynamics simulations to disclose the… (More)
DOI: 10.1371/journal.pcbi.1000306

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@article{Stacklies2009MechanicalNI, title={Mechanical Network in Titin Immunoglobulin from Force Distribution Analysis}, author={Wolfram Stacklies and M. Cristina Vega and Matthias Wilmanns and Frauke Gr{\"a}ter}, journal={PLoS Computational Biology}, year={2009}, volume={5}, pages={705 - 748} }