Mechanical Design and Analysis of a Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates.

@article{Sparrey2016MechanicalDA,
  title={Mechanical Design and Analysis of a Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates.},
  author={Carolyn J. Sparrey and Ernesto A. Aguilar Salegio and William Camisa and Horace Tam and Michael S Beattie and J C Bresnahan},
  journal={Journal of neurotrauma},
  year={2016},
  volume={33 12},
  pages={
          1136-49
        }
}
Non-human primate (NHP) models of spinal cord injury better reflect human injury and provide a better foundation to evaluate potential treatments and functional outcomes. We combined finite element (FE) and surrogate models with impact data derived from in vivo experiments to define the impact mechanics needed to generate a moderate severity unilateral cervical contusion injury in NHPs (Macaca mulatta). Three independent variables (impactor displacement, alignment, and pre-load) were examined… CONTINUE READING
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