Mecanismos de rabdomiólise com as estatinas

@article{Magalhes2005MecanismosDR,
  title={Mecanismos de rabdomi{\'o}lise com as estatinas},
  author={Maria Eliane Campos Magalh{\~a}es},
  journal={Arquivos Brasileiros De Cardiologia},
  year={2005},
  volume={85}
}
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INSUFICIÊNCIA RENAL AGUDA DEVIDO À RABDOMIÓLISE
TLDR
A rabdomiolise caracteriza-se pela lesao da musculatura estriada esqueletica e, como consequencia do dano a membrana da celula muscular, ha liberacao de constituintes intracelulares, dentre eles a enzima creatina quinase (CK).
Avaliação das possíveis interações medicamentosas de inibidores da HMG-coA-redutase utilizados no tratamento da dislipidemia
TLDR
O objetivo neste artigo foi trazer, a luz da literatura, as principais interacoes medicamentosas das estatinas disponiveis para terapeutica no Pais, fazendo-se, uma abordagem analitico-discursiva de dados encontrados em bases of dados sobre medicamentsos.
Estudo caso controle de alterações de creatinofosfoquinase em usuários de um laboratório do interior do Rio Grande do Sul Case control study of creatine phosphokinase variation in patients from a clinical laboratory of Rio Grande do Sul/Brazil
Objetivo: avaliar a prevalencia de alteracoes de creatinofosfoquinase (CPK) em individuos em uso de sinvastatina, analisando os resultados dos exames bioquimicos de creatinofosfoquinase e…
Evaluación de la calidad de cápsulas de sinvastatina de farmacias magistrales
TLDR
El metodo utilizado mostro buena adecuacion para aplicacion en control of calidad, revelando the falta de calidad de capsulas de sinvastatina producidas by algunas farmacias de manipulacion.
TRATAMENTO FARMACOLÓGICO E INTERAÇÕES MEDICAMENTOSAS EM PACIENTES COM ANEURISMA DA AORTA ABDOMINAL
TLDR
There are few data in the literature about the treatment and drug interactions in patients with AAA, and the purpose of this review is to describe pharmacotherapy and the interactions drugs in patients.
Hypolipidemic effect of β-caryophyllene to treat hyperlipidemic rats
TLDR
The results indicate that β-caryophyllene can be used to treat dyslipidemic diseases because it exerts a similar effect as the reference drug, protecting the liver against lipid damage and improving the hepatic antioxidant defense system.
Assessment of the quality of simvastatin capsules from compounding pharmacies.
TLDR
The method used was shown to be suitable for application to quality control, and it revealed the poor quality of the simvastatin capsules produced by some compounding pharmacies.
Adverse events caused by potential drug-drug interactions in an intensive care unit of a teaching hospital
TLDR
It is demonstrated that antimicrobial drugs are frequently prescribed in intensive care units and present a very high number of potential drug-drug interactions, with most of them being considered highly significant.
Biochemical markers of muscular damage
TLDR
Total antioxidant status can be used to evaluate the level of stress in muscle by other markers, such as thiobarbituric acid-reactive substances, malondialdehyde, sulfhydril groups, reduced glutathione, oxidized glutathion, superoxide dismutase, catalase and others.
Statin Therapy and Tendon Disorders
TLDR
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, a precursor of cholesterol, is studied for its role in cholesterol biosynthesis and inhibition.
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