Mebeverine alters small bowel motility in irritable bowel syndrome.

  title={Mebeverine alters small bowel motility in irritable bowel syndrome.},
  author={Peter C. Evans and Young Tae Bak and John E. Kellow},
  journal={Alimentary pharmacology & therapeutics},
  volume={10 5},
BACKGROUND AND AIM Despite its widespread use in irritable bowel syndrome (IBS), limited clinical data exist on the effects of mebeverine hydrochloride on gastrointestinal motility. Human motor activity in the small bowel is more reproducible than that in the large bowel; therefore the aim of this study was to determine in the small bowel the effects of oral mebeverine in both IBS patients and in healthy controls. METHODS Twelve IBS patients (11 females/1 male, 46 +/- 13 years old… CONTINUE READING
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