Measuring response in the gastrointestinal tract in systemic sclerosis.

  title={Measuring response in the gastrointestinal tract in systemic sclerosis.},
  author={Dinesh Khanna and Vivek Nagaraja and Heather S Gladue and William Chey and Mark Pimentel and Tracy M. Frech},
  journal={Current opinion in rheumatology},
  volume={25 6},
PURPOSE OF REVIEW Gastrointestinal tract (GIT) involvement in systemic sclerosis (scleroderma, SSc) is the most common internal complication. This review discusses the outcome measures to capture GIT involvement in clinical care and trials. RECENT FINDINGS Patient-reported outcome measures have been validated (UCLA Scleroderma Clinical Trial Consortium GIT 2.0 and NIH PROMIS scales) in SSc-GIT. Multiple objective measures are available to assess mucosal involvement and motility in GIT… CONTINUE READING
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