Measuring protein concentrations by NMR spectroscopy.

  title={Measuring protein concentrations by NMR spectroscopy.},
  author={Gerhard Wider and Lars Dreier},
  journal={Journal of the American Chemical Society},
  volume={128 8},
In applications of NMR to biological macromolecules in solution, the concentration of the NMR sample is an important parameter describing the sample and providing information for the selection and planning of experiments. Although concentrations can be measured directly by NMR spectroscopy, other methods are usually preferred to measure the concentration of macromolecules in NMR samples. The reasons are the difficulties in the correlation of the sample of interest with the signal intensity… CONTINUE READING
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