Measuring memory-prediction errors and their consequences in youth at risk for schizophrenia.

@article{Keefe2009MeasuringME,
  title={Measuring memory-prediction errors and their consequences in youth at risk for schizophrenia.},
  author={Richard S. E. Keefe and Michael S. Kraus},
  journal={Annals of the Academy of Medicine, Singapore},
  year={2009},
  volume={38 5},
  pages={414-6}
}
The largely consistent columnar circuitry observed throughout the cortex may serve to continuously predict bottom-up activation based on invariant memories. This "memory-prediction" function is essential to efficient and accurate perception. Many of the defined cognitive deficits associated with schizophrenia suggest a breakdown of memory-prediction function. As deficits in memory-prediction function are proposed to lie more proximal to the biological causes of schizophrenia than deficits in… CONTINUE READING

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