Measuring kinetic drivers of pneumolysin pore structure

  title={Measuring kinetic drivers of pneumolysin pore structure},
  author={Robert J C Gilbert and Andreas F.-P. Sonnen},
  booktitle={European Biophysics Journal},
Most membrane attack complex-perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins are thought to form pores in target membranes by assembling into pre-pore oligomers before undergoing a pre-pore to pore transition. Assembly during pore formation is into both full rings of subunits and incomplete rings (arcs). The balance between arcs and full rings… CONTINUE READING