Measuring interval cancers in population-based screening using different assays of fecal occult blood testing: the District of Florence experience.

@article{Zappa2001MeasuringIC,
  title={Measuring interval cancers in population-based screening using different assays of fecal occult blood testing: the District of Florence experience.},
  author={Marco Zappa and Guido Castiglione and Enrico Paci and Grazia Grazzini and Tiziana Rubeca and Patricia Turco and Emanuele Crocetti and Stefano Ciatto},
  journal={International journal of cancer},
  year={2001},
  volume={92 1},
  pages={151-4}
}
The fecal occult blood test (FOBT) has demonstrated its efficacy in reducing mortality from colorectal cancer (CRC). The guaiac-based FOBT has been criticized for its low sensitivity. In this study, two different assays for FOBT (guaiac or an immunochemical test based on reversed passive hemagglutination [RPHA]) were tested for comparison within a population-based screening program for colorectal cancer in the province of Florence (Italy). The proportional incidence method was used to calculate… CONTINUE READING

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