Measuring genome conservation across taxa: divided strains and united kingdoms

@article{Kunin2005MeasuringGC,
  title={Measuring genome conservation across taxa: divided strains and united kingdoms},
  author={Victor Kunin and Dag G. Ahr{\'e}n and Leon Goldovsky and Paul Jan\ssen and Christos A. Ouzounis},
  journal={Nucleic Acids Research},
  year={2005},
  volume={33},
  pages={616 - 621}
}
Species evolutionary relationships have traditionally been defined by sequence similarities of phylogenetic marker molecules, recently followed by whole-genome phylogenies based on gene order, average ortholog similarity or gene content. Here, we introduce genome conservation--a novel metric of evolutionary distances between species that simultaneously takes into account, both gene content and sequence similarity at the whole-genome level. Genome conservation represents a robust distance… CONTINUE READING
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