Measuring behavioral and endocrine responses to novelty stress in adult zebrafish

  title={Measuring behavioral and endocrine responses to novelty stress in adult zebrafish},
  author={Jonathan M. Cachat and Adam Stewart and Leah E Grossman and Siddharth Gaikwad and Ferdous Kadri and Kyung Min Chung and Nadine Wu and Keith H.K. Wong and Sudipta Roy and Christopher N Suciu and Jason Goodspeed and Marco F Elegante and Brett K Bartels and Salem I Elkhayat and David Tien and Julia Tan and Ashley Denmark and Thomas Gilder and Evan J Kyzar and John Dileo and Kevin Frank and Katie Chang and Eli Utterback and Peter Hart and Allan Kalueff},
  journal={Nature Protocols},
Several behavioral assays are currently used for high-throughput neurophenotyping and screening of genetic mutations and psychotropic drugs in zebrafish (Danio rerio). In this protocol, we describe a battery of two assays to characterize anxiety-related behavioral and endocrine phenotypes in adult zebrafish. Here, we detail how to use the 'novel tank' test to assess behavioral indices of anxiety (including reduced exploration, increased freezing behavior and erratic movement), which are… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
117 Citations
91 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 117 extracted citations


Publications referenced by this paper.
Showing 1-10 of 91 references

Deconstructing adult zebrafish behavior with swim trace visualizations

  • Cachat, J.M
  • In Zebrafish Neurobehavioral Protocols
  • 2010

Measuring endocrine (cortisol) responses of zebrafish to stress

  • Canavello, P.R
  • Zebrafish Neurobehavioral Protocols
  • 2010

Similar Papers

Loading similar papers…