Measuring CamKII activity in Xenopus embryos as a read-out for non-canonical Wnt signaling.

@article{Khl2008MeasuringCA,
  title={Measuring CamKII activity in Xenopus embryos as a read-out for non-canonical Wnt signaling.},
  author={Michael K{\"u}hl and Petra Pandur},
  journal={Methods in molecular biology},
  year={2008},
  volume={468},
  pages={173-86}
}
It has been known for quite some time that not all members of the Wnt family induce the formation of a secondary body axis when ectopically expressed in Xenopus embryos. An ingenious hypothesis led to the discovery that some Wnt ligands have the capacity to elicit intracellular Ca2+ signaling. This finding has been studied in more detail in the past years, which has revealed an intriguing complexity of Wnt signaling. The significance of a Wnt-induced Ca(2+)-mediated pathway during development… CONTINUE READING

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