Measuring Airway Remodeling in Patients With Different COPD Staging Using Endobronchial Optical Coherence Tomography.

@article{Ding2016MeasuringAR,
  title={Measuring Airway Remodeling in Patients With Different COPD Staging Using Endobronchial Optical Coherence Tomography.},
  author={Ming Ding and Yan Chen and Wei-Jie Guan and Chang-hao Zhong and Mei Jiang and Wei-zhan Luo and Xiaobo Chen and Chun-li Tang and Yan Tang and Qi-Ming Jian and Wei Wang and Shiyue Li and Nan-shan Zhong},
  journal={Chest},
  year={2016},
  volume={150 6},
  pages={1281-1290}
}
BACKGROUND Although FEV1 remains the gold standard for staging COPD, the association between airway remodeling and airflow limitation remains unclear. Endobronchial optical coherence tomography (EB-OCT) was performed to assess the association between disorders of large and medium to small airways and COPD staging. We also evaluated small airway architecture in heavy smokers with normal FEV1 (SNL) and healthy never-smokers. METHODS We recruited 48 patients with COPD (stage I, n = 14; stage II… CONTINUE READING
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